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Jin Bu Huan [ Lycopodium serratum ] typically used as an herbal sedative, has been reported to cause acute hepatitis [45]
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Specifically, plasma levels of GSH-conjugated APAP metabolite levels, including APAP GSH , APAP Cys , and APAP Nac , were markedly reduced in HuR Hep-/- mice 2 hours after APAP overdose, whereas levels of the major non-GSH-dependent metabolites, APAP Gluc and APAP Sulf , were comparable between genotypes
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