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If these observations are validated in future clinical studies, this SNP signal might represent a potential biomarker for risk of acetaminophen hepatotoxicity
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Glycogen synthase kinase-3β (GSK3β) and protein kinase A (PKA) have been shown to be involved in the phosphorylation of tau proteins, which are in turn important in microtubule assembly and the synaptic plasticity and function of neurons (Kolarova et al., 2012)
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