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Nitrogen Monoxide (NO)-Mediated Iron Release from Cells Is Linked to NO-Induced Glutathione Efflux via Multidrug Resistance-Associated Protein 1
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While you’re not likely to run into MPTP (unless you’re taking synthetic street drugs), it is chemically similar to a commonly used herbicide called paraquat.[ref] Subsequently, a number of studies have shown that higher paraquat exposure increases the risk of Parkinson’s disease.[ref] Monoamine Oxidase increases ROS: When monoamine oxidase breaks down a monoamine (neurotransmitters, tyramine, etc.), the reaction produces hydrogen peroxide and possibly ammonia, which are reactive oxygen species (ROS)
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