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The active site responsible for the carbon dioxide reduction is identical to the FDHs’ one and harbors one molybdenum or tungsten ion coordinated by the cis -dithiolene group of two pyranopterin cofactor molecules, one terminal sulfido group (Mo 6+ /W 6+ =S), plus one selenium or one sulfur atom from a selenocysteine or cysteine residue (Figure 1)
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