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In-vitro studies demonstrated that quercetin is a potent scavenger of ROS and reactive nitrogen species, whereas the few available in-vivo studies attributed to quercetin antiinflammatory and antioxidant activities in diseases involving ROS
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Furthermore, in both HFD-induced obese mice and LPS-stimulated Caco-2 cells, IM38 increased the levels of TJ proteins (ZO-1, occludin, and claudin-1) in the colon [92]
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