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The synergistic potential of immunotherapy can be explored: PCBP1 has been reported as a potential target for immunotherapy, but whether ACE-induced ferroptosis enhances the antitumor immune response through the release of damage-associated molecular patterns (DAMPs) remains to be verified

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In the same vein, hepatic DAG contents and PKCε translocation to the plasma membrane were shown to be more potent predictors of hepatic insulin resistance than other factors such as ceramide, endoplasmic reticulum (ER) stress marker, and inflammatory cytokine levels in humans [106,110,111]