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Because NNMT consumes nicotinamide, blocking the enzyme preserves more nicotinamide for the NAD+ salvage pathway, increasing intracellular NAD+ concentration in treated cell models
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[DOI] [PubMed] [Google Scholar] 47.Maecker H, Jonnalagadda V, Bhakta S, Jammalamadaka V, Junutula JR
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