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24 VEGF-A111, excluding exons 5–7, diffuses easily, resists proteolysis, and is induced by DNA damage, 27 while VEGF-A121, lacking exons 6A and 7, is soluble, forming stable homodimers resilient to oxidative stress
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The liquid chromatography (LC) gradient program was: 98% B for 1 minute, followed by a linear decrease to 40% B within 5 minutes, then maintaining 40% B for 13 minutes, then returning to 98% B in 1 minute and finally 5 minutes 98% B for column equilibration
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