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*Journal of Clinical Endocrinology & Metabolism*, 96(7), 1911-1930
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5-Amino-1MQ is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed at high levels in adipose tissue and liver that depletes the cell's nicotinamide and methyl-donor reserves — both needed for NAD+ synthesis
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