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The animal studies are reassuring as far as they go: the 2018 work reported no observed adverse effects at its tested dose, and the 2024 study reported normalised liver enzymes rather than raised ones, which is the opposite of a hepatic safety signal
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IGF-1 regulates PEAR1 through Egr1 to promote skeletal muscle post-injury regeneration [PMID: 41506419] Laboratory literature summary: IGF-1 regulates PEAR1 through Egr1 to promote skeletal muscle post-injury regeneration
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