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Distant metastasis and progression: Breast cancer metastasis is a complex, multicellular, and highly regulated process involving local invasion of primary tumor cells, epithelial-to-mesenchymal transition, invasion into the bloodstream, survival of tumor cells in the circulatory system, and colonization of secondary distant sites

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Alternatives to PPIs Collectively, these and many other studies suggest that PPIs are not as safe as they are made out to be