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When EAAT1 (SLC1A3) is knocked out in mice, they are more susceptible to neuronal death from concussions and are also susceptible to retinal degeneration
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Hydrogenolytic debenzylation preceded oxidation of the hydroxymethyl group to afford diester (4 R ,5 S )- 21 which after hydrolysis gave (2 R ,3 S )- 2 as the hydrochloride (Scheme 5) [53]
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