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Although NAFLD is closely associated with metabolic factors such as obesity and insulin resistance, the specific mechanisms underlying its progression, especially from steatosis to hepatitis, fibrosis and cirrhosis, remain an area requiring further investigation (18, 19)
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Mutations in the LRRK2 gene are linked to PD, with missense mutations resulting in increased autophosphorylation and substrate phosphorylation of LRRK2
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