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Microglia-astrocyte crosstalk contributes to astrocyte activation in MS Astrocytes are central figures in the signaling milieu during neuroinflammation, modulating peripheral immune infiltration and chronic tissue inflammation (reviewed in 145 )
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The proliferative phase follows, characterized by the formation of new blood vessels (angiogenesis), production of granulation tissue rich in collagen and new capillaries, and migration of cells to fill the wound space
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