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Furthermore, the problems associated with vitamin C and E derivatives (e.g., limited tissue retention, targeting to the active site of oxidative stress, no targeting to specific ROS, and poor interaction with specific carriers) will largely also apply to these substances (especially because they structurally resemble vitamin C and E and share similar mechanisms of action)
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For patients whose primary concern is dehydration, a dedicated IV hydration therapy session may be a more focused option
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