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In addition, exercise-induced ROS stimulate mitochondrial biogenesis by activating PGC-1Ξ±, which is involved in the production of new mitochondria, as reported by Halling and Pilegaard [198]
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Although the same unlabeled oligonucleotide substrates competed efficiently with labelled substrate for extension, no reduction of activity was observed when the double-stranded blunt-ended hairpin oligonucleotides were used as competitors, even in the presence of 100-fold excess hairpins
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