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doi: 10.1093/nar/gkaa804 92 KohJHJohnsonMLDasariSLeBrasseurNKVuckovicIHendersonGCet al

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As mentioned in other inflammatory‐mediated disorders, the utility and or efficacy of VNS may be predicated on treating early in disease progression, as noted above, most positive pre‐clinical VNS effects are dependent on administration of VNS prior to the disease injury, that is, AKI in this case