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2) This study performed by researchers Heffernan et al explored the chronic and acute metabolic effects of AOD9604 in several mouse models, including lean C57BL/6J, ob/ob, WT, and β3-KO mice
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This experience-dependent neural plasticity mechanism is thought to require a rapid, state-dependent system capable of dynamically adapting to prior synaptic activity to maintain network stability and promote persistent changes such as long-term potentiation (LTP) or long-term depression (LTD) (Abraham, 2008)
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