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Article References Running Head: Oxidants and Antioxidants Funding Support: This study was supported by the National Science Center, Poland (grant 2015/17/B/NZ5/01370)

Women's Health

Size:200ml

patients with symptomatic decline (poor sleep, body composition changes, reduced energy) may be candidates • Patients with body composition goals where GH optimization is clinically relevant: body fat accumulation alongside lean mass reduction that has not responded adequately to lifestyle intervention • Individuals seeking sleep quality improvement where GH-axis optimization is part of the clinical picture • Athletes or active individuals with recovery requirements where GH-mediated protein synthesis is a clinical priority • Patients already in a comprehensive longevity program where GH-axis assessment and optimization is part of the protocol The decision to prescribe Ipamorelin or any GH secretagogue begins with a clinical assessment that includes baseline IGF-1 measurement (the primary marker of GH axis activity), review of the patient's symptom profile, and evaluation of contraindications