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The migration and tube formation ability of HUVECs are observed to be enhanced significantly after addition LRG1, whereas the load-induced hypertrophic scar formation resulted from pathological angiogenesis is ameliorated after depletion of LRG1 (Zhang et al., 2019)
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It holds a licensed indication for HIV-associated lipodystrophy in the United States (FDA approval, 2010)
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