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each state is stabilized by a different ligand interaction determining whether a peptide works as an agonist or antagonist (Xue et al., 2025)

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In vitro biostability of M-CuP and D-CuP against Proteinase K 1 mM D-CuP and 2 mM M-CuP aqueous solutions (1 mL) were incubated separately with Proteinase K (10 U mL −1 , 100 µL) at 37 °C for 0, 1, 2 and 4 h