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What remains true is that the IV route delivers a known, immediate dose into the blood without depending on gut handling — which is exactly why many providers who use glutathione clinically still prefer it

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As stated previously, if we did not take the above into account, into our estimate of total FY 2025 payments would be too low, and, as a result, our outlier threshold would be too high, such that estimated outlier payments would be less than our projected 5.14 percent of total payments (which reflects the estimate of outlier reconciliation calculated for this final rule)