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Nevertheless, contemporary investigations have indicated that APOE stimulates the PI3K/AKT signaling cascade to suppress ferroptosis, consequently hindering iron-catalyzed lipid peroxidation ( 9 Targeting ferroptosis to treat AD Up to now, drug-based interventions crafted for Alzheimer’s pathology remain non-remedial, yet they succeed in easing the clinical manifestations of the disorder (Long and Holtzman, 2019)
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Longer term For longer or repeated cycles, review trends every 3-6 months with a clinician because long-term human safety data are limited
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