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Compared with cystine starvation or FIN treatment, GSH depletion generally results in much milder ferroptosis phenotype (or even does not induce obvious cell death in some cell lines) 12 , indicating that there might exist additional mechanisms linking SLC7A11-mediated cystine transport to GPX4 function in ferroptosis regulation
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In terms of therapeutics, while nutritional supplements are not cures for ASD, our review suggests they have a role as adjunctive treatments
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