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In summary, clinical trial design must take into account the dual role of bilirubin, including formulating a rigorous dose escalation scheme, stratifying patients based on UGT1A1 genotype, and simultaneously monitoring signs of both efficacy and bilirubin neurotoxicity
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Enzymatic Synthesis of ω-Hydroxydodecanoic Acid By Employing a Cytochrome P450 from Limnobacter Sp
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