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FIGURE 1 The prevalence of DED, which surged to as high as 61.0% during the COVID-19 pandemic (Ji et al., 2023), underscores the influence of increased exposure to visual display terminals and widespread mask usage during the pandemic, which likely exacerbated the condition by decreasing blink frequency and increasing thermal air currents over the ocular area, thus enhancing tear evaporation rates (Uwimana et al., 2022

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Pathological Hallmarks of Alzheimer Disease A formal diagnosis of AD requires the presence of both senile plaques, which are composed of aggregated fibrils of Aβ (mostly 42 and 40 amino acids in length) together with dystrophic neurites and neurofibrillary tangles, which are composed of aggregates of hyperphosphorylated Tau protein (98, 99)