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L-theanine can alleviate the immune stress response caused by LPS, maintain the α1-acid glycoprotein (α1-AGP) and IL-6 concentrations in serum, and the secretory immunoglobulin A (sIgA) content in the jejunal mucosa [75], inhibit the infection and survival of coccidia in vivo, and improve the non-specific immune response of chickens [76]

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In a large in-vitro screen of 500 medicinal herbs, the aqueous extract of Gotu Kola ranked among the top 13 with strong anti–HSV-2 activity (virus inhibition log ≥4.0), providing early evidence that Centella asiatica contains potent antiviral compounds [35] In cultured monkey kidney (Vero) cells infected with HSV-1 and HSV-2, crude water extracts of Gotu Kola and Mango (Mangifera indica L.) both blocked viral plaque formation and reduced production of infectious virions