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31 , 32 Phosphorothioates, in which sulfur replaces a non-bridging oxygen, perform better: translational output increases 2-fold, while stability rises 6- to 8-fold, and the stereopure Sp isomer evades recognition by IFIT1, thereby dampening innate immune sensing
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Scaling up photobioreactors to very large volumes can be challenging due to engineering and cost constraints [100]
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