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Frontiers | Excessive alcohol consumption: a driver of metabolic dysfunction and inflammation
The two-electron oxidation of a thiol(ate) residue by reactive oxygen or nitrogen species, such as H 2 O 2 or peroxynitrite, yields a cysteine-sulfenic acid (SOH) intermediate that is highly reactive and metastable [15,75]
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Measurement:10 kg
This single intervention would achieve greater reduction in population carcinogenic exposure than any other measure discussed in this chapter
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