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Considerations specific to adolescents include: Assessment of pubertal development and growth The family’s ability to support long-term dietary, supplement, and follow-up needs Psychological readiness, including the young person’s own understanding and consent Awareness that weight regain in late adolescence and early adulthood is possible Nutritional supervision through adolescence, when nutrient needs are high Long-term studies suggest that adolescents who undergo bariatric surgery have meaningful improvements in weight, type 2 diabetes, blood pressure, and quality of life, with safety profiles similar to adults
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ApoE-targeting increases the transfer of solid lipid nanoparticles with donepezil cargo across a culture model of the blood-brain barrier
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