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Compounds in VAC binds to dopamine type 2 (DA-2) receptors in the CNS, decreasing cAMP and prolactin release (94)
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Nonetheless, α-KG competitors (DM-succinate and ITA) inhibit the YBX1–AMPK axis in both cancer cells and 293T cells, suggesting that α-KG availability may broadly determines energy sensing in human cells
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