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LL-37 also inhibits the NLRP3 inflammasome — a multiprotein complex that when chronically activated in aging tissue generates IL-1β and IL-18, two of the most potent pro-inflammatory cytokines associated with neurodegeneration and cardiovascular disease
photo damage or prevent ageing
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Additionally, the risk is 20 times higher among individuals with a body mass index (BMI) greater than 35 kg/m2
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