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Activities of target proliferation-associated genes (Bmpr1a, Igf1, Itgb2, Jag1, and Pdgfc) are intricately linked to the regulation of the cell cycle via Nrf2 (91).The induction of G2/M phase arrests in the absence of Nrf2 indicates that Nrf2 is an essential regulator of the cell cycle through its control of inhibitory cell-cycle regulators (92)
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