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However, it is noteworthy that, while upregulation of glutamine metabolism is a phenomenon present in many cancer cells, recent studies have shown a decrease in glutamine metabolism in cholangiocarcinoma, glioblastoma multiforme, liver hepatocellular carcinoma, and thyroid carcinoma, demonstrating tissue heterogeneity in glutamine metabolism [40]
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Figure 3C), and APOB (Figure 3E) and significantly increased levels of ABCG5 (Figure 3F), ABCG8 (Figure 3G), and low-density lipoprotein receptor (LDLR
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