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Therefore, a group of rats were administered diethylmaleate (DEM) intrarectally and mucosal samples were taken at 1, 4 and 24 hours to examine the levels of GSH and appearance of injury
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continued using Bmal1 knockout mice and reported altered clock gene expression (Cry2 and Per2) along with decreased Nrd1, Dbp, Il1 β, and Nox2 expression and increased Gsr and Lpl expression, indicating that Bmal1 regulates immune response and cellular metabolism in microglia (Wang et al., 2020)
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