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BPC 157 in Rodent Ischemia–Reperfusion Injury: A Critical Review of Preclinical Evidence
Evidence TypeSourceStrength of EvidenceAnimal studiesRodent models for tendons, ligaments, fracturesStrongest, but not applicable to humans directlyPilot human studiesOnly 3 identified in 2026 reviewVery limitedCase series17 patients, knee injectionsLow, small sample sizeLarge clinical trialsNone currently existNot available This table shows why experts describe BPC-157 as "promising but unproven." A single case series or animal study is not enough to support routine clinical use
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NAD+ therapy restores those depleted levels directly
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