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While this paper aims to summarise the compounds that activate AMPK, directly or indirectly, it is also important to note that, AMPK activation is not the only way of regulating energy balance-related conditions [29]
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Sorafenib, a multi-kinase inhibitor approved for advanced liver and renal cancers, also demonstrates activity in breast cancer through mitophagy-mediated, ROS-driven p53 pathway activation [493]
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