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(7) Studies have shown that immune function is suppressed during pregnancy, perhaps to allow the mother’s immune system to “tolerate” the developing baby
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Further, the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) Scientific Advisory Committee and the Organisation for Economic Co-operation and Development (OECD) strongly recommends the use of serum-free, chemically-defined media formulated with non-animal alternatives to reduce variability associated with serum supplements in current and emerging in vitro methods 13,123,129
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